PSMA6 FISH Probe

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
PSMA6-20-RE 20 (40 μL) 200 μL color Request Pricing
PSMA6-20-OR 20 (40 μL) 200 μL color Request Pricing
PSMA6-20-GO 20 (40 μL) 200 μL color Request Pricing
PSMA6-20-GR 20 (40 μL) 200 μL color Request Pricing
PSMA6-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013]

Gene Details

Gene Symbol : PSMA6

Gene Name : Proteasome subunit alpha 6

Chromosome : CHR 14: 352,785,57-353,174,78

Locus : 14q13.2

Alt. Genes : LRPPRC

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