This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2011]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PSMC3IP-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
PSMC3IP-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
PSMC3IP-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
PSMC3IP-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
PSMC3IP-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Gene Symbol : PSMC3IP
Gene Name : PSMC3 interacting protein
Chromosome : CHR 17: 425,778,30-425,723,09
Locus : 17q21.2
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