This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTGDR2-20-RE | 20 (40 μL) | 200 μL |  |
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| PTGDR2-20-OR | 20 (40 μL) | 200 μL |  |
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| PTGDR2-20-GO | 20 (40 μL) | 200 μL |  |
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| PTGDR2-20-GR | 20 (40 μL) | 200 μL |  |
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| PTGDR2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]
Gene Symbol : PTGDR2
Gene Name : Prostaglandin D2 receptor 2
Chromosome : CHR 11: 608,559,70-608,509,24
Locus : 11q12.2
Alt. Genes : TRIM28
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