The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTGDS-20-RE | 20 (40 μL) | 200 μL |  |
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| PTGDS-20-OR | 20 (40 μL) | 200 μL |  |
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| PTGDS-20-GO | 20 (40 μL) | 200 μL |  |
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| PTGDS-20-GR | 20 (40 μL) | 200 μL |  |
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| PTGDS-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008]
Gene Symbol : PTGDS
Gene Name : Prostaglandin D2 synthase
Chromosome : CHR 9: 136,977,503-136,981,741
Locus : 9q34.3
Alt. Genes : ZNF197
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