Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTGS2-20-RE | 20 (40 μL) | 200 μL |  |
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| PTGS2-20-OR | 20 (40 μL) | 200 μL |  |
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| PTGS2-20-GO | 20 (40 μL) | 200 μL |  |
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| PTGS2-20-GR | 20 (40 μL) | 200 μL |  |
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| PTGS2-20-AQ | 20 (40 μL) | 200 μL |  |
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Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
Gene Symbol : PTGS2
Gene Name : Prostaglandin-endoperoxide synthase 2
Chromosome : CHR 1: 186,680,426-186,671,811
Locus : 1q31.1
Alt. Genes : OPTN
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