The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTK6-20-RE | 20 (40 μL) | 200 μL |  |
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| PTK6-20-OR | 20 (40 μL) | 200 μL |  |
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| PTK6-20-GO | 20 (40 μL) | 200 μL |  |
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| PTK6-20-GR | 20 (40 μL) | 200 μL |  |
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| PTK6-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Symbol : PTK6
Gene Name : Protein tyrosine kinase 6
Chromosome : CHR 20: 635,373,69-635,284,12
Locus : 20q13.33
Alt. Genes : RASA4
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