The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTPN14-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PTPN14-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PTPN14-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PTPN14-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PTPN14-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010]
Gene Symbol : PTPN14
Gene Name : Protein tyrosine phosphatase, non-receptor type 14
Chromosome : CHR 1: 214,551,680-214,348,695
Locus : 1q32.3-q41
Alt. Genes : HIPK3
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.