The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTPN3-20-RE | 20 (40 μL) | 200 μL |  |
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| PTPN3-20-OR | 20 (40 μL) | 200 μL |  |
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| PTPN3-20-GO | 20 (40 μL) | 200 μL |  |
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| PTPN3-20-GR | 20 (40 μL) | 200 μL |  |
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| PTPN3-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Gene Symbol : PTPN3
Gene Name : Protein tyrosine phosphatase, non-receptor type 3
Chromosome : CHR 9: 109,538,394-109,375,693
Locus : 9q31.3
Alt. Genes : ZNF263
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