This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTPRN2-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PTPRN2-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PTPRN2-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PTPRN2-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PTPRN2-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Gene Symbol : PTPRN2
Gene Name : Protein tyrosine phosphatase, receptor type N2
Chromosome : CHR 7: 158,587,801-157,539,051
Locus : 7q36.3
Alt. Genes : RBM12
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.