This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PUF60-20-RE | 20 (40 μL) | 200 μL |  |
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| PUF60-20-OR | 20 (40 μL) | 200 μL |  |
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| PUF60-20-GO | 20 (40 μL) | 200 μL |  |
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| PUF60-20-GR | 20 (40 μL) | 200 μL |  |
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| PUF60-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Gene Symbol : PUF60
Gene Name : Poly(U) binding splicing factor 60
Chromosome : CHR 8: 143,829,385-143,816,343
Locus : 8q24.3
Alt. Genes : PREB
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