Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM, May 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PUS10-20-RE | 20 (40 μL) | 200 μL |  |
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| PUS10-20-OR | 20 (40 μL) | 200 μL |  |
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| PUS10-20-GO | 20 (40 μL) | 200 μL |  |
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| PUS10-20-GR | 20 (40 μL) | 200 μL |  |
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| PUS10-20-AQ | 20 (40 μL) | 200 μL |  |
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Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM, May 2009]
Gene Symbol : PUS10
Gene Name : Pseudouridylate synthase 10
Chromosome : CHR 2: 610,182,82-609,383,51
Locus : 2p16.1-p15
Alt. Genes : ENAM
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