The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PVR-20-RE | 20 (40 μL) | 200 μL |  |
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| PVR-20-OR | 20 (40 μL) | 200 μL |  |
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| PVR-20-GO | 20 (40 μL) | 200 μL |  |
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| PVR-20-GR | 20 (40 μL) | 200 μL |  |
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| PVR-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Gene Symbol : PVR
Gene Name : Poliovirus receptor
Chromosome : CHR 19: 446,437,97-446,661,60
Locus : 19q13.31
Alt. Genes : STAG1
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