This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAD1-20-RE | 20 (40 μL) | 200 μL |  |
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| RAD1-20-OR | 20 (40 μL) | 200 μL |  |
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| RAD1-20-GO | 20 (40 μL) | 200 μL |  |
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| RAD1-20-GR | 20 (40 μL) | 200 μL |  |
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| RAD1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009]
Gene Symbol : RAD1
Gene Name : RAD1 checkpoint DNA exonuclease
Chromosome : CHR 5: 349,156,74-349,052,59
Locus : 5p13.2
Alt. Genes : RAD50
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