The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAD21-20-RE | 20 (40 μL) | 200 μL |  |
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| RAD21-20-OR | 20 (40 μL) | 200 μL |  |
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| RAD21-20-GO | 20 (40 μL) | 200 μL |  |
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| RAD21-20-GR | 20 (40 μL) | 200 μL |  |
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| RAD21-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008]
Gene Symbol : RAD21
Gene Name : RAD21 cohesin complex component
Chromosome : CHR 8: 116,874,865-116,845,933
Locus : 8q24.11
Alt. Genes : ARPC2
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