RAD51B FISH Probe

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
RAD51B-20-RE 20 (40 μL) 200 μL color Request Pricing
RAD51B-20-OR 20 (40 μL) 200 μL color Request Pricing
RAD51B-20-GO 20 (40 μL) 200 μL color Request Pricing
RAD51B-20-GR 20 (40 μL) 200 μL color Request Pricing
RAD51B-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016]

Gene Details

Gene Symbol : RAD51B

Gene Name : RAD51 paralog B

Chromosome : CHR 14: 678,197,78-686,831,17

Locus : 14q24.1

Alt. Genes : CLEC3A

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