RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).[supplied by OMIM, Nov 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RALBP1-20-RE | 20 (40 μL) | 200 μL |  |
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| RALBP1-20-OR | 20 (40 μL) | 200 μL |  |
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| RALBP1-20-GO | 20 (40 μL) | 200 μL |  |
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| RALBP1-20-GR | 20 (40 μL) | 200 μL |  |
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| RALBP1-20-AQ | 20 (40 μL) | 200 μL |  |
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RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).[supplied by OMIM, Nov 2010]
Gene Symbol : RALBP1
Gene Name : RalA binding protein 1
Chromosome : CHR 18: 947,553,1-953,810,7
Locus : 18p11.22
Alt. Genes : SGK2
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