This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAPGEF1-20-RE | 20 (40 μL) | 200 μL |  |
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| RAPGEF1-20-OR | 20 (40 μL) | 200 μL |  |
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| RAPGEF1-20-GO | 20 (40 μL) | 200 μL |  |
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| RAPGEF1-20-GR | 20 (40 μL) | 200 μL |  |
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| RAPGEF1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Symbol : RAPGEF1
Gene Name : Rap guanine nucleotide exchange factor 1
Chromosome : CHR 9: 131,740,067-131,576,769
Locus : 9q34.13
Alt. Genes : OPTN
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