The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RASGRP2-20-RE | 20 (40 μL) | 200 μL |  |
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| RASGRP2-20-OR | 20 (40 μL) | 200 μL |  |
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| RASGRP2-20-GO | 20 (40 μL) | 200 μL |  |
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| RASGRP2-20-GR | 20 (40 μL) | 200 μL |  |
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| RASGRP2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Gene Symbol : RASGRP2
Gene Name : RAS guanyl releasing protein 2
Chromosome : CHR 11: 647,454,55-647,269,10
Locus : 11q13.1
Alt. Genes : HNRNPA3P1
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