This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RASSF5-20-RE | 20 (40 μL) | 200 μL |  |
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| RASSF5-20-OR | 20 (40 μL) | 200 μL |  |
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| RASSF5-20-GO | 20 (40 μL) | 200 μL |  |
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| RASSF5-20-GR | 20 (40 μL) | 200 μL |  |
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| RASSF5-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : RASSF5
Gene Name : Ras association domain family member 5
Chromosome : CHR 1: 206,507,529-206,589,283
Locus : 1q32.1
Alt. Genes : ZNF263
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