This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RASSF8-20-RE | 20 (40 μL) | 200 μL |  |
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| RASSF8-20-OR | 20 (40 μL) | 200 μL |  |
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| RASSF8-20-GO | 20 (40 μL) | 200 μL |  |
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| RASSF8-20-GR | 20 (40 μL) | 200 μL |  |
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| RASSF8-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Gene Symbol : RASSF8
Gene Name : Ras association domain family member 8
Chromosome : CHR 12: 259,590,30-260,798,91
Locus : 12p12.1
Alt. Genes : LINC01587
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