This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RBBP5-20-RE | 20 (40 μL) | 200 μL |  |
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| RBBP5-20-OR | 20 (40 μL) | 200 μL |  |
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| RBBP5-20-GO | 20 (40 μL) | 200 μL |  |
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| RBBP5-20-GR | 20 (40 μL) | 200 μL |  |
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| RBBP5-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010]
Gene Symbol : RBBP5
Gene Name : RB binding protein 5, histone lysine methyltransferase complex subunit
Chromosome : CHR 1: 205,122,021-205,086,141
Locus : 1q32.1
Alt. Genes : FEM1B
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