NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
RELA-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
RELA-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
RELA-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
RELA-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
RELA-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Symbol : RELA
Gene Name : RELA proto-oncogene, NF-kB subunit
Chromosome : CHR 11: 656,629,71-656,535,95
Locus : 11q13.1
Alt. Genes : CEBPZ
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