This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described [provided by RefSeq, Jul 2010]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
REST-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
REST-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
REST-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
REST-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
REST-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described [provided by RefSeq, Jul 2010]
Gene Symbol : REST
Gene Name : RE1 silencing transcription factor
Chromosome : CHR 4: 569,078,75-569,358,46
Locus : 4q12
Alt. Genes : ENAM
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