RFC2 FISH Probe

This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2. [provided by RefSeq, Jul 2013]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
RFC2-20-RE 20 (40 μL) 200 μL color Request Pricing
RFC2-20-OR 20 (40 μL) 200 μL color Request Pricing
RFC2-20-GO 20 (40 μL) 200 μL color Request Pricing
RFC2-20-GR 20 (40 μL) 200 μL color Request Pricing
RFC2-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2. [provided by RefSeq, Jul 2013]

Gene Details

Gene Symbol : RFC2

Gene Name : Replication factor C subunit 2

Chromosome : CHR 7: 742,544,57-742,315,01

Locus : 7q11.23

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