The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RFC3-20-RE | 20 (40 μL) | 200 μL |  |
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| RFC3-20-OR | 20 (40 μL) | 200 μL |  |
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| RFC3-20-GO | 20 (40 μL) | 200 μL |  |
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| RFC3-20-GR | 20 (40 μL) | 200 μL |  |
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| RFC3-20-AQ | 20 (40 μL) | 200 μL |  |
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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : RFC3
Gene Name : Replication factor C subunit 3
Chromosome : CHR 13: 338,180,48-339,739,45
Locus : 13q13.2
Alt. Genes : SGK2
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