This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RGCC-20-RE | 20 (40 μL) | 200 μL |  |
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| RGCC-20-OR | 20 (40 μL) | 200 μL |  |
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| RGCC-20-GO | 20 (40 μL) | 200 μL |  |
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| RGCC-20-GR | 20 (40 μL) | 200 μL |  |
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| RGCC-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq, Jul 2008]
Gene Symbol : RGCC
Gene Name : Regulator of cell cycle
Chromosome : CHR 13: 414,574,05-414,708,76
Locus : 13q14.11
Alt. Genes : KIF20A
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