This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RGS1-20-RE | 20 (40 μL) | 200 μL |  |
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| RGS1-20-OR | 20 (40 μL) | 200 μL |  |
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| RGS1-20-GO | 20 (40 μL) | 200 μL |  |
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| RGS1-20-GR | 20 (40 μL) | 200 μL |  |
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| RGS1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]
Gene Symbol : RGS1
Gene Name : Regulator of G protein signaling 1
Chromosome : CHR 1: 192,575,726-192,580,028
Locus : 1q31.2
Alt. Genes : FAM13A
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