The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RGS13-20-RE | 20 (40 μL) | 200 μL |  |
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| RGS13-20-OR | 20 (40 μL) | 200 μL |  |
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| RGS13-20-GO | 20 (40 μL) | 200 μL |  |
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| RGS13-20-GR | 20 (40 μL) | 200 μL |  |
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| RGS13-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008]
Gene Symbol : RGS13
Gene Name : Regulator of G protein signaling 13
Chromosome : CHR 1: 192,636,137-192,660,310
Locus : 1q31.2
Alt. Genes : RBM12
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