This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RGS17-20-RE | 20 (40 μL) | 200 μL |  |
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| RGS17-20-OR | 20 (40 μL) | 200 μL |  |
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| RGS17-20-GO | 20 (40 μL) | 200 μL |  |
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| RGS17-20-GR | 20 (40 μL) | 200 μL |  |
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| RGS17-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]
Gene Symbol : RGS17
Gene Name : Regulator of G protein signaling 17
Chromosome : CHR 6: 153,131,283-153,010,890
Locus : 6q25.2
Alt. Genes : HIPK3
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