This gene encodes a protein that binds to all members of the R7 subfamily of regulators of G protein signaling and regulates their translocation between the nucleus and the plasma membrane. The encoded protein could be regulated by reversible palmitoylation, which anchors it to the plasma membrane. Depalmitoylation localizes the protein to the nucleus. Polymorphisms in this gene may be associated with risk of aspirin-exacerbated respiratory disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RGS7BP-20-RE | 20 (40 μL) | 200 μL |  |
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| RGS7BP-20-OR | 20 (40 μL) | 200 μL |  |
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| RGS7BP-20-GO | 20 (40 μL) | 200 μL |  |
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| RGS7BP-20-GR | 20 (40 μL) | 200 μL |  |
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| RGS7BP-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that binds to all members of the R7 subfamily of regulators of G protein signaling and regulates their translocation between the nucleus and the plasma membrane. The encoded protein could be regulated by reversible palmitoylation, which anchors it to the plasma membrane. Depalmitoylation localizes the protein to the nucleus. Polymorphisms in this gene may be associated with risk of aspirin-exacerbated respiratory disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2012]
Gene Symbol : RGS7BP
Gene Name : Regulator of G protein signaling 7 binding protein
Chromosome : CHR 5: 645,045,64-646,146,60
Locus : 5q12.3
Alt. Genes : FEM1B
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