This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RHOA-20-RE | 20 (40 μL) | 200 μL |  |
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| RHOA-20-OR | 20 (40 μL) | 200 μL |  |
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| RHOA-20-GO | 20 (40 μL) | 200 μL |  |
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| RHOA-20-GR | 20 (40 μL) | 200 μL |  |
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| RHOA-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
Gene Symbol : RHOA
Gene Name : Ras homolog family member A
Chromosome : CHR 3: 494,120,96-493,591,35
Locus : 3p21.31
Alt. Genes : YAF2
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