This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RHOG-20-RE | 20 (40 μL) | 200 μL |  |
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| RHOG-20-OR | 20 (40 μL) | 200 μL |  |
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| RHOG-20-GO | 20 (40 μL) | 200 μL |  |
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| RHOG-20-GR | 20 (40 μL) | 200 μL |  |
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| RHOG-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X. [provided by RefSeq, Aug 2011]
Gene Symbol : RHOG
Gene Name : Ras homolog family member G
Chromosome : CHR 11: 384,098,2-382,697,7
Locus : 11p15.4
Alt. Genes : LRPPRC
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