The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RHOH-20-RE | 20 (40 μL) | 200 μL |  |
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| RHOH-20-OR | 20 (40 μL) | 200 μL |  |
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| RHOH-20-GO | 20 (40 μL) | 200 μL |  |
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| RHOH-20-GR | 20 (40 μL) | 200 μL |  |
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| RHOH-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]
Gene Symbol : RHOH
Gene Name : Ras homolog family member H
Chromosome : CHR 4: 401,910,10-402,447,63
Locus : 4p14
Alt. Genes : LRPPRC
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