The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RIPK3-20-RE | 20 (40 μL) | 200 μL |  |
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| RIPK3-20-OR | 20 (40 μL) | 200 μL |  |
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| RIPK3-20-GO | 20 (40 μL) | 200 μL |  |
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| RIPK3-20-GR | 20 (40 μL) | 200 μL |  |
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| RIPK3-20-AQ | 20 (40 μL) | 200 μL |  |
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The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]
Gene Symbol : RIPK3
Gene Name : Receptor interacting serine/threonine kinase 3
Chromosome : CHR 14: 243,400,35-243,360,20
Locus : 14q12
Alt. Genes : LPAR6
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