This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects. [provided by RefSeq, Jul 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
RLN2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
RLN2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
RLN2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
RLN2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
RLN2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects. [provided by RefSeq, Jul 2016]
Gene Symbol : RLN2
Gene Name : Relaxin 2
Chromosome : CHR 9: 530,613,3-529,986,3
Locus : 9p24.1
Alt. Genes : CAPN9
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