This gene encodes a member of a family of RING finger domain-containing E3 ubiquitin ligases that also includes parkin and parc. The expression of this gene is induced by DNA damage. The encoded protein interacts with the cytoplasmic DNA-dependent protein kinase, catalytic subunit (DNA-PKcs) and promotes its degradation through ubiquitination. The orthologous mouse protein has been shown to interact with a ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Mar 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RNF144A-20-RE | 20 (40 μL) | 200 μL |  |
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| RNF144A-20-OR | 20 (40 μL) | 200 μL |  |
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| RNF144A-20-GO | 20 (40 μL) | 200 μL |  |
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| RNF144A-20-GR | 20 (40 μL) | 200 μL |  |
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| RNF144A-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of a family of RING finger domain-containing E3 ubiquitin ligases that also includes parkin and parc. The expression of this gene is induced by DNA damage. The encoded protein interacts with the cytoplasmic DNA-dependent protein kinase, catalytic subunit (DNA-PKcs) and promotes its degradation through ubiquitination. The orthologous mouse protein has been shown to interact with a ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Mar 2017]
Gene Symbol : RNF144A
Gene Name : Ring finger protein 144A
Chromosome : CHR 2: 691,739,1-707,688,5
Locus : 2p25.1
Alt. Genes : HIPK3
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