This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RNPS1-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| RNPS1-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| RNPS1-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| RNPS1-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| RNPS1-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Gene Symbol : RNPS1
Gene Name : RNA binding protein with serine rich domain 1
Chromosome : CHR 16: 226,841,1-225,311,5
Locus : 16p13.3
Alt. Genes : RBM12
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.