Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RRAGB-20-RE | 20 (40 μL) | 200 μL |  |
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| RRAGB-20-OR | 20 (40 μL) | 200 μL |  |
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| RRAGB-20-GO | 20 (40 μL) | 200 μL |  |
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| RRAGB-20-GR | 20 (40 μL) | 200 μL |  |
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| RRAGB-20-AQ | 20 (40 μL) | 200 μL |  |
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Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Symbol : RRAGB
Gene Name : Ras related GTP binding B
Chromosome : CHR X: 557,176,76-557,602,08
Locus : Xp11.21
Alt. Genes : LHFPL6
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