This gene encodes a protein component of the radial spoke head in flagella and motile cilia. Eukaryotic flagella and motile cilia share a common 9 + 2 structure, in which nine peripheral microtubule doublets (MTDs) surround a central-pair of microtubules (CP), with radial spokes connecting the MTDs to the CP. The radial spoke is a multi-protein complex that works as a mechanochemical transducer between the CP and the MTDs. The radial spoke contributes to the regulation of the activity of dynein motors, and thus to flagellar motility. PMID: 22754630 provides a good review of radial spokes. [provided by RefSeq, Jul 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RSPH10B2-20-RE | 20 (40 μL) | 200 μL |  |
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| RSPH10B2-20-OR | 20 (40 μL) | 200 μL |  |
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| RSPH10B2-20-GO | 20 (40 μL) | 200 μL |  |
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| RSPH10B2-20-GR | 20 (40 μL) | 200 μL |  |
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| RSPH10B2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein component of the radial spoke head in flagella and motile cilia. Eukaryotic flagella and motile cilia share a common 9 + 2 structure, in which nine peripheral microtubule doublets (MTDs) surround a central-pair of microtubules (CP), with radial spokes connecting the MTDs to the CP. The radial spoke is a multi-protein complex that works as a mechanochemical transducer between the CP and the MTDs. The radial spoke contributes to the regulation of the activity of dynein motors, and thus to flagellar motility. PMID: 22754630 provides a good review of radial spokes. [provided by RefSeq, Jul 2017]
Gene Symbol : RSPH10B2
Gene Name : Radial spoke head 10 homolog B2
Chromosome : CHR 7: 675,410,8-679,877,4
Locus : 7p22.1
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