This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RSPO2-20-RE | 20 (40 μL) | 200 μL |  |
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| RSPO2-20-OR | 20 (40 μL) | 200 μL |  |
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| RSPO2-20-GO | 20 (40 μL) | 200 μL |  |
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| RSPO2-20-GR | 20 (40 μL) | 200 μL |  |
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| RSPO2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Symbol : RSPO2
Gene Name : R-spondin 2
Chromosome : CHR 8: 108,083,684-107,899,315
Locus : 8q23.1
Alt. Genes : RAD50
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