This gene encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RSPO4-20-RE | 20 (40 μL) | 200 μL |  |
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| RSPO4-20-OR | 20 (40 μL) | 200 μL |  |
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| RSPO4-20-GO | 20 (40 μL) | 200 μL |  |
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| RSPO4-20-GR | 20 (40 μL) | 200 μL |  |
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| RSPO4-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2009]
Gene Symbol : RSPO4
Gene Name : R-spondin 4
Chromosome : CHR 20: 100,226,3-958,451
Locus : 20p13
Alt. Genes : LINC01587
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