This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RTEL1-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| RTEL1-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| RTEL1-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| RTEL1-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| RTEL1-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
Gene Symbol : RTEL1
Gene Name : Regulator of telomere elongation helicase 1
Chromosome : CHR 20: 636,578,09-636,962,52
Locus : 20q13.33
Alt. Genes : LRPPRC
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.