This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients. [provided by RefSeq, Mar 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RUBCNL-20-RE | 20 (40 μL) | 200 μL |  |
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| RUBCNL-20-OR | 20 (40 μL) | 200 μL |  |
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| RUBCNL-20-GO | 20 (40 μL) | 200 μL |  |
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| RUBCNL-20-GR | 20 (40 μL) | 200 μL |  |
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| RUBCNL-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients. [provided by RefSeq, Mar 2017]
Gene Symbol : RUBCNL
Gene Name : RUN and cysteine rich domain containing beclin 1 interacting protein like
Chromosome : CHR 13: 463,900,41-463,419,99
Locus : 13q14.13
Alt. Genes : YAF2
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