This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RUFY1-20-RE | 20 (40 μL) | 200 μL |  |
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| RUFY1-20-OR | 20 (40 μL) | 200 μL |  |
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| RUFY1-20-GO | 20 (40 μL) | 200 μL |  |
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| RUFY1-20-GR | 20 (40 μL) | 200 μL |  |
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| RUFY1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Symbol : RUFY1
Gene Name : RUN and FYVE domain containing 1
Chromosome : CHR 5: 179,550,550-179,610,025
Locus : 5q35.3
Alt. Genes : LRPPRC
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