The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| S1PR5-20-RE | 20 (40 μL) | 200 μL |  |
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| S1PR5-20-OR | 20 (40 μL) | 200 μL |  |
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| S1PR5-20-GO | 20 (40 μL) | 200 μL |  |
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| S1PR5-20-GR | 20 (40 μL) | 200 μL |  |
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| S1PR5-20-AQ | 20 (40 μL) | 200 μL |  |
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The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]
Gene Symbol : S1PR5
Gene Name : Sphingosine-1-phosphate receptor 5
Chromosome : CHR 19: 105,179,91-105,127,41
Locus : 19p13.2
Alt. Genes : PLXNC1
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