Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
SAE1-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
SAE1-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
SAE1-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
SAE1-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
SAE1-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]
Gene Symbol : SAE1
Gene Name : SUMO1 activating enzyme subunit 1
Chromosome : CHR 19: 471,307,81-472,106,35
Locus : 19q13.32
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