Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SAP18-20-RE | 20 (40 μL) | 200 μL |  |
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| SAP18-20-OR | 20 (40 μL) | 200 μL |  |
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| SAP18-20-GO | 20 (40 μL) | 200 μL |  |
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| SAP18-20-GR | 20 (40 μL) | 200 μL |  |
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| SAP18-20-AQ | 20 (40 μL) | 200 μL |  |
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Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2008]
Gene Symbol : SAP18
Gene Name : Sin3A associated protein 18
Chromosome : CHR 13: 211,405,13-211,490,84
Locus : 13q12.11
Alt. Genes : OPTN
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