This region contains a brain enhancer that likely regulates expression of the sonic hedgehog (SHH) gene, located approximately 460 kb downstream. A mutation in this sequence disrupts binding by homeobox protein SIX3 and causes holoprosencephaly (HPE). [provided by RefSeq, Sep 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SBE2-20-RE | 20 (40 μL) | 200 μL |  |
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| SBE2-20-OR | 20 (40 μL) | 200 μL |  |
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| SBE2-20-GO | 20 (40 μL) | 200 μL |  |
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| SBE2-20-GR | 20 (40 μL) | 200 μL |  |
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| SBE2-20-AQ | 20 (40 μL) | 200 μL |  |
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This region contains a brain enhancer that likely regulates expression of the sonic hedgehog (SHH) gene, located approximately 460 kb downstream. A mutation in this sequence disrupts binding by homeobox protein SIX3 and causes holoprosencephaly (HPE). [provided by RefSeq, Sep 2015]
Gene Symbol : SBE2
Gene Name : SHH brain enhancer 2
Chromosome : CHR 7: 0-0
Locus : 7q36
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