This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SCAP-20-RE | 20 (40 μL) | 200 μL |  |
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| SCAP-20-OR | 20 (40 μL) | 200 μL |  |
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| SCAP-20-GO | 20 (40 μL) | 200 μL |  |
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| SCAP-20-GR | 20 (40 μL) | 200 μL |  |
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| SCAP-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Symbol : SCAP
Gene Name : SREBF chaperone
Chromosome : CHR 3: 474,771,25-474,136,84
Locus : 3p21.31
Alt. Genes : LRPPRC
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