Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SCN4A-20-RE | 20 (40 μL) | 200 μL |  |
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| SCN4A-20-OR | 20 (40 μL) | 200 μL |  |
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| SCN4A-20-GO | 20 (40 μL) | 200 μL |  |
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| SCN4A-20-GR | 20 (40 μL) | 200 μL |  |
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| SCN4A-20-AQ | 20 (40 μL) | 200 μL |  |
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Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. [provided by RefSeq, Jul 2008]
Gene Symbol : SCN4A
Gene Name : Sodium voltage-gated channel alpha subunit 4
Chromosome : CHR 17: 639,729,17-639,385,53
Locus : 17q23.3
Alt. Genes : RBM12
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